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The National Academies is conducting a rapid expert consultation to provide an overview of current best practices and approaches for transitioning from vertically structured, disease-specific global health programs to more integrated, country-led, patient-centered health care, as well as ongoing capacity-building efforts that might inform or support these transitions. The consultation will examine illustrative models of service delivery integration, key implementation considerations—including governance, financing, workforce, data, laboratory, and surveillance infrastructure—and areas where additional evidence or experience is needed to support effective implementation.